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PY-60 [2765218-56-0]

PY-60 [2765218-56-0]

T9566
TargetMol Chemicals
Estimated Purity99.32%
Product group Chemicals
Molecular Weight313.37
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    PY-60 [2765218-56-0]
  • Delivery Days Customer
    9
  • Certification
    Research Use Only
  • Chemical Name
    PY-60
  • Estimated Purity
    99.32%
  • Molecular Formula
    C16H15N3O2S
  • Molecular Weight
    313.37
  • Scientific Description
    PY-60 can effectively activate YAP transcriptional activity against annexin A2 (ANXA2) (Kd value of 1.4 microM). PY-60 activates a pro-proliferative, YAP-dependent transcriptional program in adult animals that are able to remodel the epidermis through proliferation.
  • Shelf life instruction
    3 years
  • SMILES
    C(NCCCC1=NC=CS1)(=O)C=2C=C(ON2)C3=CC=CC=C3
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

References

  • Shalhout SZ, Yang PY, Grzelak EM, et al. YAP-dependent proliferation by a small molecule targeting annexin A2. Nat Chem Biol. 2021,17(7):767-775. doi: 10.1038/s41589-021-00755-0
    Read this paper