Western blot analysis of extracts of various cell lines using ASC / TMS1 Polyclonal Antibody.
Western blot analysis of extracts of various cell lines using ASC / TMS1 Polyclonal Antibody.
PYCARD Polyclonal Antibody
E-AB-60228
Product group Antibodies
Overview
- SupplierElabscience
- Product NamePYCARD Polyclonal Antibody
- Delivery Days Customer12
- CertificationResearch Use Only
- Scientific DescriptionThis gene encodes an adaptor protein that is composed of two protein-protein interaction domains: a N-terminal PYRIN-PAAD-DAPIN domain (PYD) and a C-terminal caspase-recruitment domain (CARD). The PYD and CARD domains are members of the six-helix bundle death domain-fold superfamily that mediates assembly of large signaling complexes in the inflammatory and apoptotic signaling pathways via the activation of caspase. In normal cells, this protein is localized to the cytoplasm; however, in cells undergoing apoptosis, it forms ball-like aggregates near the nuclear periphery. Two transcript variants encoding different isoforms have been found for this gene.
- UNSPSC12352203