Pyrene-PEG2-azide [2135330-58-2]

MedChem Express

Pyrene-PEG2-azide [2135330-58-2]

5

2135330-58-2

CHEMICAL,general_chemicals_reagents

Research Use Only

C23H22N4O3

402.45

Pyrene-PEG2-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Pyrene-PEG2-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

O=C(NCCOCCOCCN=[N+]=[N-])C1=CC=C2C=CC3=CC=CC4=CC=C1C2=C43

12352005