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Pyridostatin (hydrochloride)

HY-15176A
MedChem Express
CAS Number1781882-65-2
DownloadMSDS
Product group Chemicals
Estimated Purity98.53
Molecular Weight778.94
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Pyridostatin (hydrochloride) [1781882-65-2]
  • Delivery Days Customer
    10
  • CAS Number
    1781882-65-2
  • Certification
    Research Use Only
  • Estimated Purity
    98.53
  • Molecular Formula
    C31H37Cl5N8O5
  • Molecular Weight
    778.94
  • Scientific Description
    Pyridostatin (RR82) hydrochloride is a G-quadruplex DNA stabilizing agent ( K d =490 nM) and can target DNA and RNA G4s in cells. Pyridostatin hydrochloride promotes growth arrest in human cancer cells by inducing replication- and transcription-dependent DNA damage. Pyridostatin hydrochloride targets the proto-oncogene Src. Pyridostatin hydrochloride reduced SRC protein levels and SRC-dependent cellular motility in human breast cancer cells [1] [2] .
  • SMILES
    O=C(C1=CC(OCCN)=CC(C(NC2=NC3=C(C(OCCN)=C2)C=CC=C3)=O)=N1)NC4=CC(OCCN)=C5C=CC=CC5=N4.Cl.Cl.Cl.Cl.Cl
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352200