Pyridoxal isonicotinoyl hydrazone [737-86-0]

MedChem Express

Pyridoxal isonicotinoyl hydrazone [737-86-0]

10

737-86-0

Research Use Only

99.96

C14H14N4O3

286.29

Pyridoxal isonicotinoyl hydrazone is an orally active and lipophilic iron-specific chelator that acts as a non-competitive inhibitor of ferrochelatase (FECH) by binding iron ions. Pyridoxal isonicotinoyl hydrazone disrupts heme biosynthesis, leading to reduced FECH stability and increased protoporphyrin IX (PPIX) accumulation. Pyridoxal isonicotinoyl hydrazone is promising for research of iron-overload diseases (e.g., beta-thalassemia)[1][2][3][4][5][6].

CC1=NC=C(C(/C=N/NC(C2=CC=NC=C2)=O)=C1O)CO

2°C to 8°C

12352200