Pyrimidine-indole hybrid [441742-93-4]
HY-118295
CAS Number441742-93-4
Product group Chemicals
Molecular Weight361.46
Overview
- SupplierMedChem Express
- Product NamePyrimidine-indole hybrid [441742-93-4]
- Delivery Days Customer9
- CAS Number441742-93-4
- CertificationResearch Use Only
- Molecular FormulaC20H19N5S
- Molecular Weight361.46
- Scientific DescriptionPyrimidine-indole hybrid is a compound that inhibits ciliogenesis and has the activity of antagonizing the Hedgehog signaling pathway by destabilizing microtubules. Pyrimidine-indole hybrid exerts its biological effects by inhibiting ciliogenesis and deconstructing the stable form of alpha-tubulin. Pyrimidine-indole hybrid has shown its unique mechanism of action in in vitro cell experiments and zebrafish embryo models, interfering with microtubule dynamics[1].
- SMILESCC(NC1=C2C=CC=C1)=C2/C=N/NC3=C4C5=C(SC4=NC=N3)CCCC5
- UNSPSC12352200