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Pyripyropene A [147444-03-9]

HY-117832
MedChem Express
CAS Number147444-03-9
Product group Chemicals
Estimated Purity99.37
Molecular Weight583.63
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Pyripyropene A [147444-03-9]
  • Delivery Days Customer
    5
  • CAS Number
    147444-03-9
  • Certification
    Research Use Only
  • Estimated Purity
    99.37
  • Molecular Formula
    C31H37NO10
  • Molecular Weight
    583.63
  • Scientific Description
    Pyripyropene A is an orally active, potent and selective sterol O-acyltransferase 2 (SOAT2)/acyl-coenzyme A:cholesterol acyltransferase 2 (ACAT2) inhibitor, with an IC50 of 0.07 microM. Pyripyropene A attenuates hypercholesterolemia and atherosclerosis in vivo[1][2][3][4].
  • SMILES
    O=C1OC(C2=CC=CN=C2)=CC3=C1[C@H](O)[C@@]4([H])[C@]([C@@H](OC(C)=O)C[C@@]5([H])[C@](C)(COC(C)=O)[C@@H](OC(C)=O)CC[C@@]54C)(C)O3
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200