
IHC-P analysis of human heart tissue using GTX46256 PDHB antibody at 1:100. Left to right:DAPI, PDHB, Merge. Low pH, heat-induced antigen retrieval method utilizing Sodium Citrate buffer was performed.
Pyruvate Dehydrogenase E1 beta subunit antibody, N-term
GTX46256
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
TargetPDHB
Overview
- SupplierGeneTex
- Product NamePyruvate Dehydrogenase E1 beta subunit antibody, N-term
- Delivery Days Customer9
- Application Supplier NoteWB: 0.2-2.5 ug/ml. IHC-P: 2-10 ug/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.5-1 mg/ml
- ConjugateUnconjugated
- Gene ID5162
- Target namePDHB
- Target descriptionpyruvate dehydrogenase E1 subunit beta
- Target synonymsepididymis secretory sperm binding protein; PDHBD; PDHE1B; PDHE1-B; PHE1B; pyruvate dehydrogenase (lipoamide) beta; pyruvate dehydrogenase E1 beta subunit; pyruvate dehydrogenase E1 component subunit beta, mitochondrial; pyruvate dehydrogenase, E1 beta polypeptide
- HostRabbit
- IsotypeIgG
- Protein IDP11177
- Protein NamePyruvate dehydrogenase E1 component subunit beta, mitochondrial
- Scientific DescriptionThe pyruvate dehydrogenase (PDH) complex is a nuclear-encoded mitochondrial multienzyme complex that catalyzes the overall conversion of pyruvate to acetyl-CoA and carbon dioxide, and provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle. The PDH complex is composed of multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). The E1 enzyme is a heterotetramer of two alpha and two beta subunits. This gene encodes the E1 beta subunit. Mutations in this gene are associated with pyruvate dehydrogenase E1-beta deficiency. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2012]
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203