PZ703b

Biorbyt

PZ703b

10

2471970-56-4

Research Use Only

C80H102CLF3N10O11S4

1600.434505

PZ703b is highly potent in killing BCL-XL dependent, BCL-2 dependent, and BCL-XL/BCL-2 dual-dependent cells in an E3 ligase (VHL)-dependent fashion.

C(N1CCN(C2C=CC(C(=O)NS(C3C=CC(N[C@@H](CSC4C=CC=CC=4)CCN4CCOCC4)=C(S(=O)(=O)C(F)(F)F)C=3)(=O)=O)=CC=2)CC1)C1C[C@](C)(CNC(=O)CCCCCCCCC(=O)N[C@@H](C(C)(C)C)C(N2C[C@H](O)C[C@H]2C(=O)N[C@H](C2C=CC(C3=C(N=CS3)C)=CC=2)C)=O)CCC=1C1C=CC(Cl)=CC=1

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