PZP antibody
GTX102547
ApplicationsWestern Blot
Product group Antibodies
TargetPZP
Overview
- SupplierGeneTex
 - Product NamePZP antibody
 - Delivery Days Customer9
 - Application Supplier NoteWB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
 - ApplicationsWestern Blot
 - CertificationResearch Use Only
 - ClonalityPolyclonal
 - Concentration0.65 mg/ml
 - ConjugateUnconjugated
 - Gene ID5858
 - Target namePZP
 - Target descriptionPZP alpha-2-macroglobulin like
 - Target synonymsC3 and PZP-like alpha-2-macroglobulin domain-containing protein 6; CPAMD6; Pregnancy zone protein; pregnancy-zone protein
 - HostRabbit
 - IsotypeIgG
 - Scientific DescriptionThe protein encoded by this gene is highly expressed in late-pregnancy serum and is similar in structure to alpha-2-macroglobulin. The encoded protein, which acts as a homotetramer, inhibits the activity of all four classes of proteinases. This protein contains cleavage sites for several proteinases. Upon binding of a proteinase, the conformation of this protein changes to trap the proteinase, limiting its activity. This protein appears to be elevated in the sera of presymptomatic Alzheimers disease patients. [provided by RefSeq, Dec 2016]
 - Storage Instruction-20°C or -80°C,2°C to 8°C
 - UNSPSC12352203
 
References
- Human pregnancy zone protein stabilizes misfolded proteins including preeclampsia- and Alzheimers-associated amyloid beta peptide. Cater JH et al., 2019 Mar 26, Proc Natl Acad Sci U S ARead more
 


