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PZP antibody

Name: PZP antibody
SKU: GTX102547_G10
Availability: BackOrder

GTX102547

ApplicationsWestern Blot

Product group Antibodies

ReactivityHuman

TargetPZP

Overview

Supplier
GeneTex
Product Name
PZP antibody
Delivery Days Customer
9
Application Supplier Note
WB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Applications
Western Blot
Certification
Research Use Only
Clonality
Polyclonal
Concentration
0.65 mg/ml
Conjugate
Unconjugated
Formulation
Liquid
Gene ID5858
Target name
PZP
Target description
PZP alpha-2-macroglobulin like
Target synonyms
C3 and PZP-like alpha-2-macroglobulin domain-containing protein 6; CPAMD6; Pregnancy zone protein; pregnancy-zone protein
Host
Rabbit
Isotype
IgG
Scientific Description
The protein encoded by this gene is highly expressed in late-pregnancy serum and is similar in structure to alpha-2-macroglobulin. The encoded protein, which acts as a homotetramer, inhibits the activity of all four classes of proteinases. This protein contains cleavage sites for several proteinases. Upon binding of a proteinase, the conformation of this protein changes to trap the proteinase, limiting its activity. This protein appears to be elevated in the sera of presymptomatic Alzheimers disease patients. [provided by RefSeq, Dec 2016]
Reactivity
Human
Storage Instruction
-20°C or -80°C,2°C to 8°C
UNSPSC
12352203

Human pregnancy zone protein stabilizes misfolded proteins including preeclampsia- and Alzheimers-associated amyloid beta peptide. Cater JH et al., 2019 Mar 26, Proc Natl Acad Sci U S A
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