Q-Plex(tm) Human Type 2 Immunity (5-Plex)

QuidelOrtho

Q-Plex(tm) Human Type 2 Immunity (5-Plex)

7

ELISA, Other Application

2.25 hours

Research Use Only

The Q-Plex™ Human Type 2 Immunity (4-Plex) is a fully quantitative plate-based multiplex ELISA for the detection of cytokines associated with type 2 immunity. Functions of type 2 immunity include protecting the host, maintaining metabolic homeostasis, suppressing type 1 inflammation, barrier defense, and tissue regeneration. Like other immune responses, excessive or chronic activation of type 2 immunity can be harmful to the host. Allergic disease, inability to defend against pathogens, and fibrosis have been described as harmful actions of type 2 immunity. Producers of type 2 cytokines include macrophages, mast cells, T cells, macrophages, monocytes, basophils, eosinophils, and natural killer cells. A variety of immune and non-immune cells have been noted to produce type 2 cytokine responses in response epithelial damage, release of alarmins, and antigen presentation/recognition.

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