QC6352
HY-104048
CAS Number1851373-36-8
Product group Chemicals
Estimated Purity99.48
Molecular Weight387.47
Overview
- SupplierMedChem Express
- Product NameQC6352 [1851373-36-8]
- Delivery Days Customer10
- CAS Number1851373-36-8
- CertificationResearch Use Only
- Estimated Purity99.48
- Molecular FormulaC24H25N3O2
- Molecular Weight387.47
- Scientific DescriptionQC6352 is an orally active KDM4 inhibitor with anti-tumor and anti-proliferative activity. QC6352 has in vivo inhibitory effects on PDX models of breast and colon cancer and reduces the number of chemoresistant cell populations. QC6352 inhibits KDM4 different isoforms with IC 50 s of 104 nM (KDM4A), 56 nM (KDM4B), 35 nM (KDM4C), and 104 nM (KDM4D), respectively. QC6352 has moderate inhibitory activity against KDM5 with an IC 50 of 750 nM (KDM5B) [1] [2] .
- SMILESO=C(C1=C(NC[C@@H]2CCCC3=C2C=CC(N(C)C4=CC=CC=C4)=C3)C=NC=C1)O
- Storage Instruction2°C to 8°C
- UNSPSC12352200