QH536 [2754254-07-2]

MedChem Express

QH536 [2754254-07-2]

10

2754254-07-2

Research Use Only

C33H49N3O3

535.76

QH536 (Compound 29) is a potent HMGCR degrader with an EC50 of 0.22 microM. QH536 has no side-effect of inducing cholesterol accumulation in cells. QH536 shows anti-inflammatory and can be used for cardiovascular disease and nonalcoholic steatohepatitis research[1].

C[C@@](C1=CC2)(CC(C=NN3C(C)=O)=C3C(C)1C)[C@](CC4)([H])[C@]2([H])[C@@](CC[C@]5([H])[C@H](C)CCC(N6CCOCC6)=O)([H])[C@]45C

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