
Western blot All lanes: QKI antibody at 1.92microg/ml Lane 1: HL60 whole cell lysate Lane 2: K562 whole cell lysate Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 38, 37, 36 kDa Observed band size: 38, 70 kDa
QKI Antibody
CSB-PA842739ESR2HU
ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
Product group Antibodies
TargetQKI
Overview
- SupplierCusabio
- Product NameQKI Antibody
- Delivery Days Customer20
- ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID9444
- Target nameQKI
- Target descriptionQKI, KH domain containing RNA binding
- Target synonymshomolog of mouse quaking QKI (KH domain RNA binding protein); Hqk; hqkI; protein quaking; QK; QK1; QK3; QKI/LOC100132735 fusion; quaking homolog, KH domain RNA binding; RNA binding protein HQK
- HostRabbit
- IsotypeIgG
- Protein IDQ96PU8
- Protein NameProtein quaking
- Scientific DescriptionRNA-binding protein that plays a central role in myelinization (PubMed:16641098). Binds to the 5-NACUAAY-N(1,20)-UAAY-3 RNA core sequence. Regulates target mRNA stability (PubMed:23630077). In addition, acts by regulating pre-mRNA splicing, mRNA export and protein translation. Required to protect and promote stability of mRNAs such as MBP and CDKN1B. Regulator of oligodendrocyte differentiation and maturation in the brain that may play a role in myelin and oligodendrocyte dysfunction in schizophrenia (PubMed:16641098). Participates in mRNA transport by regulating the nuclear export of MBP mRNA. Also involved in regulation of mRNA splicing of MAG pre-mRNA. Acts as a translational repressor (By similarity).
- Storage Instruction-20°C or -80°C
- UNSPSC12352203