QM385 [2093421-02-2]

MedChem Express

QM385 [2093421-02-2]

9

2093421-02-2

Research Use Only

99.48

C17H18F3N7O2

409.37

QM385 is a potent sepiapterin reductase (SPR) inhibitor with an IC50 of 1.49 nM, which blocks T-cell proliferation and autoimmunity at nanomolar potency and with good oral bioavailability[1].

O=C1NC(N2N=CC(C(N3CCN(CC(F)(F)F)CC3)=O)=C2C)=NN4C1=CC=C4

-20°C,2°C to 8°C

12352200