Quetiapine

MedChem Express

Quetiapine [111974-69-7]

10

111974-69-7

Research Use Only

99.88

C21H25N3O2S

383.51

Quetiapine (ICI204636) is a 5-HT receptors agonist with a pEC 50 of 4.77 for human 5-HT1A receptor. Quetiapine is a dopamine receptor antagonist with a pIC 50 of 6.33 for human D2 receptor. Quetiapine has moderate to high affinity for the human D2 , HT1A , 5-HT2A , 5-HT2C receptor with pK i s of 7.25, 5.74, 7.54, 5.55. Antidepressant and anxiolytic effects [1] .

OCCOCCN(CC1)CCN1C2=NC3=CC=CC=C3SC4=C2C=CC=C4

-20°C,2°C to 8°C

12352200