Quetiapine (hemifumarate)-d8 [1435938-24-1]

MedChem Express

Quetiapine (hemifumarate)-d8 [1435938-24-1]

10

1435938-24-1

Research Use Only

99.35

C25H21D8N3O6S

507.63

Quetiapine (hemifumarate)-d8 is the deuterium labeled Quetiapine hemifumarate[1]. Quetiapine hemifumarate is a 5-HT receptors agonist with a pEC50 of 4.77 for human 5-HT1A receptor. Quetiapine hemifumarate is a dopamine receptor antagonist with a pIC50 of 6.33 for human D2 receptor. Quetiapine hemifumarate has moderate to high affinity for the human D2, HT1A, 5-HT2A, 5-HT2C receptor with pKis of 7.25, 5.74, 7.54, 5.55. Antidepressant and anxiolytic effects[2].

OC(/C=C/C(O)=O)=O.OCCOCCN1C([2H])([2H])C([2H])([2H])N(C([2H])([2H])C1([2H])[2H])C2=NC3=CC=CC=C3SC4=CC=CC=C24

2°C to 8°C

12352200