Quinolinic acid [89-00-9]

MedChem Express

Quinolinic acid [89-00-9]

5

89-00-9

Research Use Only

99.88

h319, h335

C7H5NO4

167.12

Quinolinic acid, an endogenous metabolite of tryptophan, is a N-methyl-D-aspartate receptor (NMDA receptor) agonist. Quinolinic acid increases glutamate efflux, induces the generation of ROS, activates nitric oxide synthase, produces excessive NO, leading to calcium ion influx and neuronal apoptosis[1][2][3][4][5][6][7][8].

O=C(C1=NC=CC=C1C(O)=O)O

-20°C,2°C to 8°C

12352200