Quisinostat (dihydrochloride)

MedChem Express

Quisinostat (dihydrochloride) [875320-31-3]

10

875320-31-3

Research Use Only

99.05

C21H28Cl2N6O2

467.39

Quisinostat dihydrochloride (JNJ-26481585 dihydrochloride) is an orally available, potent pan- HDAC inhibitor with IC 50 s of 0.11 nM, 0.33 nM, 0.64 nM, 0.46 nM, and 0.37 nM for HDAC1, HDAC2, HDAC4, HDAC10 and HDAC11, respectively. Quisinostat dihydrochloride has a broad spectrum antitumoral activity [1] .

[H]Cl.O=C(C1=CN=C(N2CCC(CNCC3=CN(C)C4=C3C=CC=C4)CC2)N=C1)NO.[H]Cl

2°C to 8°C

12352200