R-1479

MedChem Express

R-1479 [478182-28-4]

10

478182-28-4

Research Use Only

99.60

C9H12N6O5

284.23

R-1479 (4-Azidocytidine), a nucleoside analogue, is a specific inhibitor of RNA-dependent RNA polymerase ( RdRp ) of HCV . R-1479 inhibits HCV replication in the HCV subgenomic replicon system ( IC 50 =1.28 microM) [1] [2] [3] . R-1479 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

OC[C@]1(N=[N+]=[N-])[C@@H](O)[C@@H](O)[C@H](N2C(N=C(N)C=C2)=O)O1

-20°C,2°C to 8°C

12352200