R 59-022

MedChem Express

R 59-022 [93076-89-2]

5

93076-89-2

Research Use Only

99.82

C27H26FN3OS

459.58

R 59-022 (DKGI-I) is a DGK inhibitor (IC50: 2.8 microM). R 59-022 inhibits the phosphorylation of OAG to OAPA. R 59-022 is a 5-HT Receptor antagonist, and activates protein kinase C (PKC). R 59-022 potentiates thrombin-induced diacylglycerol production in platelets and inhibits phosphatidic acid production in neutrophils[1][2][3][4].

O=C1C(CCN(CC/2)CCC2=C(C3=CC=CC=C3)/C4=CC=C(F)C=C4)=C(C)N=C5N1C=CS5

-20°C

12352200