R 59-022 (hydrochloride) [93076-98-3]

MedChem Express

R 59-022 (hydrochloride) [93076-98-3]

10

93076-98-3

Research Use Only

98.88

C27H27ClFN3OS

496.04

R 59-022 (DKGI-I) hydrochloride is a DGK inhibitor (IC50: 2.8 microM). R 59-022 hydrochloride inhibits the phosphorylation of OAG to OAPA. R 59-022 hydrochloride is a 5-HT Receptor antagonist, and activates protein kinase C (PKC). R 59-022 hydrochloride potentiates thrombin-induced diacylglycerol production in platelets and inhibits phosphatidic acid production in neutrophils[1][2][3][4].

O=C1C(CCN(CC/2)CCC2=C(C3=CC=CC=C3)/C4=CC=C(F)C=C4)=C(C)N=C5N1C=CS5.[H]Cl

-20°C

12352200