R-75317 [115406-25-2]
HY-119035
CAS Number115406-25-2
Product group Chemicals
Molecular Weight631.76
Overview
- SupplierMedChem Express
- Product NameR-75317 [115406-25-2]
- Delivery Days Customer9
- CAS Number115406-25-2
- CertificationResearch Use Only
- Molecular FormulaC29H50N3O8PS
- Molecular Weight631.76
- Scientific DescriptionR-75317 is a specific platelet-activating factor (PAF) antagonist. R-75317 can prevent the decline in creatinine clearance (Ccr) in a rat model of glomerulonephritis induced by the injection of antibodies extracted from rabbits against rat glomerular basement membrane (GBM) antigens, delay the onset of proteinuria, and improve glomerular hypertrophy, mesangial matrix proliferation, and interstitial fibrosis. R-75317 may be useful in the study of glomerulonephritis[1].
- SMILESCCCCCCCCCCCCCCCCCNC(OC[C@@H](OC1=NOC=C1)COP(OCC[N+]2=CSC=C2)([O-])=O)=O
- UNSPSC12352200