(R)-CE3F4 [1593478-56-8]

MedChem Express

(R)-CE3F4 [1593478-56-8]

5

1593478-56-8

Research Use Only

99.0

C11H10Br2FNO

351.01

(R)-CE3F4 is a potent and selective inhibitor of exchange protein directly activated by cAMP isoform 1 (Epac1), with an IC50 of 4.2 microM, with 10-fold selectivity for Epac1 over Epac2 (IC50, 44 microM). (R)-CE3F4 is more potent than racemic CE3F4 and (S)-CE3F4[1].

O=CN1[C@H](C)CCC2=C1C=C(Br)C(F)=C2Br

-20°C

12352200