(R)-Coriolic acid [10219-69-9]

MedChem Express

(R)-Coriolic acid [10219-69-9]

5

10219-69-9

Research Use Only

C18H32O3

296.44

(R)-Coriolic acid (13(R)-HODE) is the opposite enantiomer of the 13(S)-HODE produced when linoleic acid is incubated with soybean lipoxygenase. The presence of 13(R)-HODE in the supernatants and membranes of cultured bovine endothelial cells has been attributed to COX metabolism. 13(R)-HODE is a weak (IC50=2.7 microM) inhibitor of U-46619-induced platelet aggregation.

CCCCC[C@@H](O)/C=C/C=C\CCCCCCCC(O)=O

12352200