(R)-Elagolix
M30666
CAS Number834153-87-6
Product group Chemicals
Molecular Weight631.59
Overview
- SupplierAbMole BioScience
- Product Name(R)-Elagolix
- Delivery Days Customer9
- CAS Number834153-87-6
- Category SupplierChemical
- CertificationResearch Use Only
- Molecular FormulaC32H30F5N3O5
- Molecular Weight631.59
- Scientific DescriptionElagolix is a highly potent, selective, orally-active, short-duration, non-peptide antagonist of the gonadotropin-releasing hormone receptor (GnRHR) (KD = 54 pM). Target: GnRH in vitro: Elagolix is a short-acting, nonpeptide, GnRH antagonist, administered orally, that unlike injectable depot GnRH agonists and antagonists, produces a dose-dependent suppression of ovarian estrogen production, that is, from partial suppression at lower doses to full suppression at higher doses. Elagolix is regarded as the frontrunner of a new class of GnRH inhibitors that have been denoted as second-generation, due to their non-peptide nature and oral bioavailability.
- UNSPSC12352200