(R)-GNE-140

MedChem Express

(R)-GNE-140 [2003234-63-5]

5

2003234-63-5

Research Use Only

99.73

C25H23ClN2O3S2

499.04

(R)-GNE-140 is a potent lactate dehydrogenase A ( LDHA ) inhibitor, with IC 50 s of 3 nM and 5 nM for LDHA and LDHB, respectively; (R)-GNE-140 is 18-fold more potent than S enantiomer.

O=C1N[C@@](C2=CSC=C2)(C3=CC=C(N4CCOCC4)C=C3)CC(O)=C1SC5=CC=CC=C5Cl

-20°C,2°C to 8°C

12352200