R-HP210

MedChem Express

R-HP210

10

Research Use Only

98.21

C22H19N3O2S2

421.54

R-HP210 acts on the NF-kappaB mediated tethered transrepression function (IC50=3.80 microM). R-HP210 represses the LPS-induced transcription of a variety of proinflammatory genes such as IL-1beta, IL-6 and COX-2. R-HP210 does not induce the transactivation functions of Glucocorticoids (GCs)[1].

C[C@H](C1=CC=CC=C1)NC(C2=CC=C(C=C2)CN3C(C4=C(NC3=S)C=CS4)=O)=O

-20°C

12131703