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(R)-JNJ-31020028

HY-107479
MedChem Express
CAS Number1094873-17-2
Product group Chemicals
Molecular Weight565.68
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Overview

  • Supplier
    MedChem Express
  • Product Name
    (R)-JNJ-31020028 [1094873-17-2]
  • Delivery Days Customer
    10
  • CAS Number
    1094873-17-2
  • Certification
    Research Use Only
  • Molecular Formula
    C34H36FN5O2
  • Molecular Weight
    565.68
  • Scientific Description
    (R)-JNJ-31020028 is a high affinity, selective brain penetrant neuropeptide Y Y2 receptor antagonist, with pIC 50 values of 8.07, 8.22 and 8.21 for human, rat, and mouse Y2 receptor, respectively. (R)-JNJ-31020028 shows >100-fold selective versus human Y1, Y4, and Y5 receptors. (R)-JNJ-31020028 has antidepressant like effects [1] [2] .
  • SMILES
    O=C(N(CC)CC)[C@@H](C1=CC=CC=C1)N2CCN(C3=CC=C(NC(C4=CC=CC=C4C5=CC=CN=C5)=O)C=C3F)CC2
  • UNSPSC
    12352200