R18 [211364-78-2]

TargetMol Chemicals

R18 [211364-78-2]

16

211364-78-2

Chemical

Research Use Only

R18

C101H157N27O29S3

2309.69

Antagonist of 14.3.3 proteins (KD ~80 nM). Competitively inhibits 14.3.3-ligand interactions without requiring phosphorylation. Blocks the ability of 14.3.3 to bind to target proteins such as Raf-1, Bad, ASK1 and exoenzyme S.

3 years

C([C@@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(=O)N1[C@H](C(O)=O)CCC1)CC(C)C)=O)CS)=O)CCSC)=O)CC(N)=O)=O)C)=O)CCC(O)=O)=O)CC(C)C)=O)CC(O)=O)=O)CC(C)C)=O)NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(=O)[C@H]2N(C([C@@H](NC([C@@H](NC([C@H](CC3=CN=CN3)NC(=O)[C@@H]4CCCN4)=O)CS)=O)[C@@H](C)C)=O)CCC2)CCCNC(=N)N)=O)CC(O)=O)=O)CC(C)C)=O)CO)=O)C=5C=6C(NC5)=CC=CC6

-20°C

12352200