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R59949

HY-108355
MedChem Express
CAS Number120166-69-0
DownloadMSDS
Product group Chemicals
Estimated Purity99.08
Molecular Weight489.58
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Overview

  • Supplier
    MedChem Express
  • Product Name
    R59949 [120166-69-0]
  • Delivery Days Customer
    10
  • CAS Number
    120166-69-0
  • Certification
    Research Use Only
  • Estimated Purity
    99.08
  • Molecular Formula
    C28H25F2N3OS
  • Molecular Weight
    489.58
  • Scientific Description
    R59949 is a pan diacylglycerol kinase (DGK) inhibitor with an IC50 of 300 nM. R59949 strongly inhibits the activity of type I DGK alpha and gamma and moderately attenuates the activity of type II DGK theta and kappa. R59949 activates protein kinase C (PKC) by enhancing the levels of the endogenous ligand diacyl glycerol[1][2][3].
  • SMILES
    O=C1N(CCN2CC/C(CC2)=C(C3=CC=C(F)C=C3)\C4=CC=C(F)C=C4)C(NC5=C1C=CC=C5)=S
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

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