R82913 [126347-69-1]

MedChem Express

R82913 [126347-69-1]

9

126347-69-1

Research Use Only

C16H20ClN3S

321.87

R82913 (9-Cl-TIBO) is a potent and high selective inhibitor of HIV-1 reverse transcriptase with antiviral activity on both an RNA template (negative strand synthesis) and a DNA template (positive strand synthesis). R82913 inhibits the replication of different strains of HIV-I in CEM cells with a median IC50 value of of 0.15 microM[1][2].

S=C1N2C3=C(C=C(C=C3N1)Cl)CN([C@H](C2)C)C/C=C(C)\C

12352200