RAB8A antibody, C-term

GeneTex

RAB8A antibody, C-term

7

WB: 0.1-0.3microg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot

Research Use Only

Polyclonal

0.50 mg/ml

Unconjugated

RAB8A

RAB8A, member RAS oncogene family

MEL, RAB8, ras-related protein Rab-8A, mel transforming oncogene (RAB8 homolog), mel transforming oncogene (derived from cell line NK14), mel transforming oncogene (derived from cell line NK14)- RAB8 homolog, oncogene c-mel, ras-associated protein RAB8

Goat

IgG

Ras-related protein Rab-8A

The protein encoded by this gene is a member of the RAS superfamily which are small GTP/GDP-binding proteins with an average size of 200 amino acids. The RAS-related proteins of the RAB/YPT family may play a role in the transport of proteins from the endoplasmic reticulum to the Golgi and the plasma membrane. This protein shares 97%, 96%, and 51% similarity with the dog RAB8, mouse MEL, and mouse YPT1 proteins, respectively and contains the 4 GTP/GDP-binding sites that are present in all the RAS proteins. The putative effector-binding site of this protein is similar to that of the RAB/YPT proteins. However, this protein contains a C-terminal CAAX motif that is characteristic of many RAS superfamily members but which is not found in YPT1 and the majority of RAB proteins. Although this gene was isolated as a transforming gene from a melanoma cell line, no linkage between MEL and malignant melanoma has been demonstrable. This oncogene is located 800 kb distal to MY09B on chromosome 19p13.1. [provided by RefSeq, Jul 2008]

-20°C or -80°C,2°C to 8°C

12352203