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ProductsBack/Rabbit anti Human Sirt1 Protein (Human)

Rabbit anti Human Sirt1 Protein (Human)

Research Use Only
X2739P
Nordic-MUbio
ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetSIRT1
Price on request
100 ug
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More than 130 suppliers
ISO certified
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Overview

  • Supplier
    Nordic-MUbio
  • Product Name
    Rabbit anti Human Sirt1 Protein (Human)
  • Delivery Days Customer
    7
  • Application Supplier Note
    Optimal concentration should be evaluated by serial dilutions.
  • Applications
    Western Blot, ELISA, ImmunoHistoChemistry
  • Applications Supplier
    Immunohistochemistry;Western Blotting;ELISA;Western Blotting
  • Category Supplier
    Primary antibodies
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Estimated Purity
    >95%
  • Gene ID23411
  • Target name
    SIRT1
  • Target description
    sirtuin 1
  • Target synonyms
    NAD-dependent protein deacetylase sirtuin-1; NAD-dependent protein deacylase sirtuin-1; regulatory protein SIR2 homolog 1; SIR2; SIR2alpha; SIR2L1; SIR2-like protein 1; sirtuin type 1
  • Host
    Rabbit
  • Protein IDQ96EB6
  • Protein Name
    NAD-dependent protein deacetylase sirtuin-1
  • Scientific Description
    NAD-dependent deacetylase sirtuin-1, hSIRT1, SIR2-like protein 1, hSIR2, SIRT1, SIR2L1
  • Shelf life instruction
    See expiration date on vial
  • Reactivity
    Human
  • Reactivity Supplier
    Human
  • Reactivity Supplier Note
    Synthetic Peptide near C terminal of human Sirt 1
  • UNSPSC
    12352203

References

  • 1. SIRT1 induces EMT by cooperating with EMT transcription factors and enhances prostate cancer cell migration and metastasis. Byles V, Zhu L, Lovaas JD, Chmilewski LK, Wang J, Faller DV, Dai Y. Oncogene. 2012 Jan 16. doi: 10.1038/onc.2011.612. 2. SIRT1 activates MAO-A in the brain to mediate anxiety and exploratory drive. Libert S, Pointer K, Bell EL, Das A, Cohen DE, Asara JM, Kapur K, Bergmann S, Preisig M, Otowa T, Kendler KS, Chen X, Hettema JM, van den Oord EJ, Rubio JP, Guarente L. Cell. 2011 Dec 23;147(7):1459-72. Epub 2011 Dec 8. 3. Role of SIRT1 in heat stress- and lipopolysaccharide-induced immune and defense gene expression in human dental pulp cells. Lee SI, Min KS, Bae WJ, Lee YM, Lee SY, Lee ES, Kim EC. J Endod. 2011 Nov;37(11):1525-30. Epub 2011 Sep 9. 4. p53 deacetylation by SIRT1 decreases during protein kinase CKII downregulation-mediated cellular senescence. Jang SY, Kim SY, Bae YS. FEBS Lett. 2011 Nov 4;585(21):3360-6. Epub 2011 Sep 29. 5. SIRT1 deacetylates the DNA methyltransferase 1 (DNMT1) protein and alters its activities. Peng L, Yuan Z, Ling H, Fukasawa K, Robertson K, Olashaw N, Koomen J, Chen J, Lane WS, Seto E. Mol Cell Biol. 2011 Dec;31(23):4720-34. Epub 2011 Sep 26 6. SIRT1 is essential for oncogenic signaling by estrogen/estrogen receptor alfa in breast cancer. Elangovan S, Ramachandran S, Venkatesan N, Ananth S, Gnana-Prakasam JP, Martin PM, Browning DD, Schoenlein PV, Prasad PD, Ganapathy V, Thangaraju M. Cancer Res. 2011 Nov 1;71(21):6654-64. Epub 2011 Sep 15. 7. Roles of SIRT1 in high glucose-induced endothelial impairment: association with diabetic atherosclerosis. Yang J, Wang N, Zhu Y, Feng P. Arch Med Res. 2011 Jul;42(5):354-60. doi: 10.1016/j.arcmed.2011.07.005. Epub 2011 Jul 31. 8. Sirt1 deacetylates c-Myc and promotes c-Myc/Max association. Mao B, Zhao G, Lv X, Chen HZ, Xue Z, Yang B, Liu DP, Liang CC. Int J Biochem Cell Biol. 2011 Nov;43(11):1573-81. Epub 2011 Jul 22.