(Rac)-AB-423 [422547-55-5]
HY-112142A
CAS Number422547-55-5
Product group Chemicals
Molecular Weight386.39
Overview
- SupplierMedChem Express
- Product Name(Rac)-AB-423 [422547-55-5]
- Delivery Days Customer9
- CAS Number422547-55-5
- CertificationResearch Use Only
- Molecular FormulaC17H17F3N2O3S
- Molecular Weight386.39
- Scientific Description(Rac)-AB-423 (DVR-23) is an anti-HBV candidate compound with promising anti-HBV activity. (Rac)-AB-423 showed no induction of CYP1A2, CYP3A4, or CYP2B6 enzyme activity at high concentrations. (Rac)-AB-423 exhibited desirable pharmacokinetic properties, enabling good systemic exposure and high oral bioavailability. (Rac)-AB-423 achieved more than 2 log viral load reduction in the hydrodynamic injection (HDI) HBV mouse model[1].
- SMILESO=C(NC1=CC=C(F)C(F)=C1)C2=CC(S(=O)(NC(C)CC)=O)=CC=C2F
- UNSPSC12352200