(Rac)-ALX 5407

MedChem Express

(Rac)-ALX 5407 [405225-21-0]

10

405225-21-0

Research Use Only

C24H24FNO3

393.45

NFPS is a selective, non-competitive glycine transporter-1 (GlyT1) inhibitor with IC 50 s of 2.8 nM and 9.8 nM for hGlyT1 and rGlyT1, respectively [1] . NFPS exerts neuroprotection via glyR alpha1 subunit in the rat model of transient focal cerebral ischaemia and reperfusion [2] .

OC(CN(C)CCC(C1=CC=C(F)C=C1)OC2=CC=C(C3=CC=CC=C3)C=C2)=O

12352200