(Rac)-Bedaquiline [654655-80-8]

MedChem Express

(Rac)-Bedaquiline [654655-80-8]

10

654655-80-8

Research Use Only

C32H31BrN2O2

555.50

(Rac)-Bedaquiline is the racemate of Bedaquiline. Bedaquiline (TMC207) is a diarylquinoline agent and inhibits Mycobacterium tuberculosis (Mtb) F1FO-ATP synthase through targeting both the c- and the epsilon-subunit. Bedaquiline has uncoupler activity. Bedaquiline is used for the multi-agent resistant tuberculosis[1][2].

BrC1=CC=C(N=C(OC)C(C(C(CCN(C)C)(O)C2=CC=CC3=C2C=CC=C3)C4=CC=CC=C4)=C5)C5=C1

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