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(Rac)-BL-918 [2435589-07-2]

(Rac)-BL-918 [2435589-07-2]

T12662
TargetMol Chemicals
CAS Number2435589-07-2
Product group Chemicals
Molecular Weight533.44
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    (Rac)-BL-918 [2435589-07-2]
  • Delivery Days Customer
    10
  • CAS Number
    2435589-07-2
  • Certification
    Research Use Only
  • Chemical Name
    (Rac)-BL-918
  • Molecular Formula
    C23H15F8N3OS
  • Molecular Weight
    533.44
  • Scientific Description
    (Rac)-BL-918 is the racemate of BL-918, a potent activator of UNC-51-like kinase 1 (ULK1) with an EC50 of 24.14 nM, inducing cytoprotective autophagy for Parkinsons disease treatment [1].
  • Shelf life instruction
    3 years
  • SMILES
    Fc1ccc(NC(=O)C(NC(=S)Nc2cc(cc(c2)C(F)(F)F)C(F)(F)F)c2ccccc2)c(F)c1
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

References

  • Ouyang L, Zhang L, Zhang S, et al. Small-Molecule Activator of UNC-51-Like Kinase 1 (ULK1) That Induces Cytoprotective Autophagy for Parkinson's Disease Treatment. J Med Chem. 2018,61(7):2776-2792. doi: 10.1021/acs.jmedchem.7b01575
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MSDS

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