(Rac)-Calpain Inhibitor XII [181769-57-3]

MedChem Express

(Rac)-Calpain Inhibitor XII [181769-57-3]

9

181769-57-3

Research Use Only

99.04

C26H34N4O5

482.57

(Rac)-Calpain Inhibitor XII is a reversible and selective inhibitor of calpain I (micro-calpain, Ki=19 nM). (Rac)-Calpain Inhibitor XII has lower affinities for calpain II (m-calpain, Ki=120 nM) and cathepsin B (Ki=750 nM). (Rac)-Calpain Inhibitor XII has the potential for studying the role of calpains in diverse processes, including neutrophil chemotaxis, neuronal signaling, and cardiac response to injury[1].

O=C(OCC1=CC=CC=C1)NC(C(NC(C(C(NCC2=NC=CC=C2)=O)=O)CCC)=O)CC(C)C

-20°C

12352200