(Rac)-CCT 250863 [1364269-06-6]

MedChem Express

(Rac)-CCT 250863 [1364269-06-6]

5

1364269-06-6

Research Use Only

99.50

C24H25F3N4O2S

490.54

(Rac)-CCT 250863 (compound rac-21) is a selective and reversible NEK 2 inhibitor with an IC50 of 0.073 microM. (Rac)-CCT 250863 shows good effects of inducing cell cycle arrest and also can antiproliferative in cells (Pomalidomide sensitive/resistant). (Rac)-CCT 250863 induces apoptosis when combines with Pomalidomide[1][2].

O=C(N)C1=CC=C(C2=CC(C3=CC(CN(C)C)=CS3)=CN=C2N)C=C1OC(C)/C=C\C(F)(F)F

-20°C,2°C to 8°C

12352200