(Rac)-Efavirenz [177530-93-7]

MedChem Express

(Rac)-Efavirenz [177530-93-7]

5

177530-93-7

Research Use Only

C14H9ClF3NO2

315.67

(Rac)-Efavirenz is the isomer of Efavirenz (HY-10572). Efavirenz (DMP 266) is a potent inhibitor of the wild-type HIV-1 reverse transcriptase with a Ki of 2.93 nM and exhibits an IC95 of 1.5 nM for the inhibition of HIV-1 replicative spread in cell culture[1].

O=C1OC(C2=CC(Cl)=CC=C2N1)(C(F)(F)F)C#CC3CC3

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