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(Rac)-Efavirenz-d4

HY-10572BS
MedChem Express
CAS Number1246812-58-7
Product group Chemicals
Molecular Weight319.70
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Overview

  • Supplier
    MedChem Express
  • Product Name
    (Rac)-Efavirenz-d4 [1246812-58-7]
  • Delivery Days Customer
    10
  • CAS Number
    1246812-58-7
  • Certification
    Research Use Only
  • Molecular Formula
    C14H5D4ClF3NO2
  • Molecular Weight
    319.70
  • Scientific Description
    (Rac)-Efavirenz-d 4 is a labelled racemic Efavirenz. Efavirenz (DMP 266) is a potent inhibitor of the wild-type HIV-1 reverse transcriptase with a Ki of 2.93 nM and exhibits an IC95 of 1.5 nM for the inhibition of HIV-1 replicative spread in cell culture[1]. (Rac)-Efavirenz-d4 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
  • SMILES
    C(#CC1C(C1([2H])[2H])([2H])[2H])C2(C(F)(F)F)C=3C(NC(=O)O2)=CC=C(Cl)C3
  • UNSPSC
    12352200