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(Rac)-SAR131675 [1092539-44-0]

(Rac)-SAR131675 [1092539-44-0]

T3691
TargetMol Chemicals
CAS Number1092539-44-0
DownloadMSDS
Product group Chemicals
Estimated Purity98.34%
Molecular Weight358.39
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    (Rac)-SAR131675 [1092539-44-0]
  • Delivery Days Customer
    9
  • CAS Number
    1092539-44-0
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    (Rac)-SAR131675
  • Estimated Purity
    98.34%
  • Molecular Formula
    C18H22N4O4
  • Molecular Weight
    358.39
  • Scientific Description
    (Rac)-SAR131675 is an effective and specific VEGFR-3 inhibitor. It inhibited VEGFR-3 tyrosine kinase activity (IC50: 20 nmol/L) and VEGFR-3 autophosphorylation (IC50: 45 nmol/L) in HEK cells, respectively. SAR131675 is highly specific for VEGFR-3 versus 107 receptors, enzymes, ion channels, and 65 kinases. SAR131675 is a highly specific VEGFR-3-TK inhibitor with significant antitumoral and antimetastatic activities in vivo through inhibition of lymphangiogenesis and TAM invasion.
  • Shelf life instruction
    3 years
  • SMILES
    CCn1c(N)c(C(=O)NC)c(=O)c2ccc(nc12)C#C[C@@](C)(O)COC
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

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Chemical Structure
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