(Rac)-Tavapadon [1643462-64-9]

MedChem Express

(Rac)-Tavapadon [1643462-64-9]

9

1643462-64-9

Research Use Only

99.87

C19H16F3N3O3

391.34

(Rac)-Tavapadon ((Rac)-PF-06649751) is a potent and selective noncatechol dopamine D1 receptor agonist. (Rac)-Tavapadon displays potent full agonism in the GS activation assay as well as partial agonism in the beta-arrestin2 recruitment assay (GS-cAMP, EC50=0.8 nM; beta-arrestin2, EC50=68 nM). (Rac)-Tavapadon has antiparkinsonian activity[1].

O=C1NC(C(C)=C(C2=CC=C(OC3=NC=CC=C3C(F)(F)F)C=C2C)N1C)=O

-20°C,2°C to 8°C

12352200