
WB analysis of human thymus (A) and tonsil (B) lysate using GTX22244 RAC2 antibody. Dilution : 0.1microg/ml Loading : 35microg protein in RIPA buffer
RAC2 antibody
GTX22244
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
TargetRAC2
Overview
- SupplierGeneTex
- Product NameRAC2 antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 0.1-0.3microg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.50 mg/ml
- ConjugateUnconjugated
- Gene ID5880
- Target nameRAC2
- Target descriptionRac family small GTPase 2
- Target synonymsEN-7; Gx; HSPC022; IMD73A; IMD73B; IMD73C; p21-Rac2; ras-related C3 botulinum toxin substrate 2; ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2); Ras-related C3 botulinum toxin substrate 3 (rho family, small GTP-binding protein Rac2); small G protein
- HostGoat
- IsotypeIgG
- Protein IDP15153
- Protein NameRas-related C3 botulinum toxin substrate 2
- Scientific DescriptionThis gene encodes a member of the Ras superfamily of small guanosine triphosphate (GTP)-metabolizing proteins. The encoded protein localizes to the plasma membrane, where it regulates diverse processes, such as secretion, phagocytosis, and cell polarization. Activity of this protein is also involved in the generation of reactive oxygen species. Mutations in this gene are associated with neutrophil immunodeficiency syndrome. There is a pseudogene for this gene on chromosome 6. [provided by RefSeq, Jul 2013]
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- AKT-mediated regulation of polarization in differentiated human neutrophil-like HL-60 cells. Zou W et al., 2012 Aug, Inflamm ResRead more
- Involvement of Rac GTPase activation in phosphatidylcholine hydroperoxide-induced THP-1 cell adhesion to ICAM-1. Asai A et al., 2011 Mar 11, Biochem Biophys Res CommunRead more
- Specific roles of Rac1 and Rac2 in motile functions of HT1080 fibrosarcoma cells. Niggli V et al., 2009 Sep 4, Biochem Biophys Res CommunRead more