WB analysis of A549 whole cell lysate using GTX00886 RAD18 antibody. The lower thick band is native Rad18 and the upper thin band is mono-ubiquitinated Rad18. Dilution : 1:1000
WB analysis of A549 whole cell lysate using GTX00886 RAD18 antibody. The lower thick band is native Rad18 and the upper thin band is mono-ubiquitinated Rad18. Dilution : 1:1000
RAD18 antibody - Orthogonal Validated
GTX00886
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry
Product group Antibodies
ReactivityHuman
TargetRAD18
Overview
- SupplierGeneTex
- Product NameRAD18 antibody - Orthogonal Validated
- Delivery Days Customer9
- ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID56852
- Target nameRAD18
- Target descriptionRAD18 E3 ubiquitin protein ligase
- Target synonymsE3 ubiquitin-protein ligase RAD18; hHR18; hRAD18; postreplication repair protein hRAD18p; postreplication repair protein RAD18; RAD18 homolog; RAD18, S. cerevisiae, homolog; RING finger protein 73; RING-type E3 ubiquitin transferase RAD18; RNF73
- HostRabbit
- IsotypeIgG
- Scientific DescriptionThe protein encoded by this gene is highly similar to S. cerevisiae DNA damage repair protein Rad18. Yeast Rad18 functions through its interaction with Rad6, which is an ubiquitin-conjugating enzyme required for post-replication repair of damaged DNA. Similar to its yeast counterpart, this protein is able to interact with the human homolog of yeast Rad6 protein through a conserved ring-finger motif. Mutation of this motif results in defective replication of UV-damaged DNA and hypersensitivity to multiple mutagens. [provided by RefSeq, Jul 2008]
- ReactivityHuman
- Storage Instruction2°C to 8°C,-20°C or -80°C
- UNSPSC12352203