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RAD54L antibody [N1N2-2], N-term

GTX100624
GeneTex
ApplicationsWestern Blot
Product group Antibodies
ReactivityHuman
TargetRAD54L
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Overview

  • Supplier
    GeneTex
  • Product Name
    RAD54L antibody [N1N2-2], N-term
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Western Blot
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.55 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID8438
  • Target name
    RAD54L
  • Target description
    RAD54 like
  • Target synonyms
    DNA repair and recombination protein RAD54-like; hHR54; HR54; hRAD54; RAD54 homolog; RAD54A
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ92698
  • Protein Name
    DNA repair and recombination protein RAD54-like
  • Scientific Description
    The protein encoded by this gene belongs to the DEAD-like helicase superfamily, and shares similarity with Saccharomyces cerevisiae Rad54, a protein known to be involved in the homologous recombination and repair of DNA. This protein has been shown to play a role in homologous recombination related repair of DNA double-strand breaks. The binding of this protein to double-strand DNA induces a DNA topological change, which is thought to facilitate homologous DNA paring, and stimulate DNA recombination. Alternative splicing results in multiple transcript variants encoding the same protein.
  • Reactivity
    Human
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • YM155 and BIRC5 downregulation induce genomic instability via autophagy-mediated ROS production and inhibition in DNA repair. Cheng SM et al., 2021 Apr, Pharmacol Res
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