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Rademikibart

Research Use Only
M54551
AbMole BioScience
Product group Antibodies
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More than 130 suppliers
ISO certified
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Overview

  • Supplier
    AbMole BioScience
  • Product Name
    Rademikibart
  • Delivery Days Customer
    9
  • Category Supplier
    Antibody
  • Certification
    Research Use Only
  • Scientific Description
    Rademikibart is a human IgG4ҡ monoclonal antibody that targets IL-4 Ralfa to block inflammatory signaling induced by IL-4 and IL-13, two important cytokines that drive allergic inflammation, and binds to the human IL-4Ralfa epitope with a KD of 20.7 pM. Rademikibart does not bind to IL-4Ralfa from other species. Rademikibart does not bind to IL-4Ralfa of other species.Rademikibart inhibits IL-4 and IL-13-mediated STAT6 signaling, TF-1 cell proliferation, and TARC production in PBMC, and can be used in studies related to moderate-to-severe Th2 inflammatory diseases.
  • UNSPSC
    12352203