RafRBD (c-Raf), Ras Binding Domain of Raf, c-Raf 1 Kinase, human, recombinant, E. coli

Jena Bioscience

RafRBD (c-Raf), Ras Binding Domain of Raf, c-Raf 1 Kinase, human, recombinant, E. coli

5

Research Use Only

Raf is a member of the serine/threonine proteine kinase family involved in regulation of cell growth and differentiation and is the most important effector of Ras. Full-length Raf is composed of three conserved regions responsible for interaction with Ras, for phosphorylation and for catalytic activity. RafRBD (Ras binding domain, amino acids 50-132) mediates interaction with membrane-anchored Ras necessary for activation of the kinase activity of Raf.

-80°C

41116133