RAGE/SERT-IN-1 [2766739-35-7]

MedChem Express

RAGE/SERT-IN-1 [2766739-35-7]

10

2766739-35-7

Research Use Only

C38H41ClN4OS

637.28

RAGE/SERT-IN-1 is a potent and orally active advanced glycation end products (RAGE) and serotonin transporter (SERT) inhibitor with IC50s of 8.26 microM and 31.09 nM, respectively. RAGE/SERT-IN-1 exhibits significant neuroprotective effect against Abeta25-35-induced neuronal damage and alleviates depressive behavior of mice. RAGE/SERT-IN-1 can be used for researching the comorbidity of Alzheimers disease and depression[1].

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