RAGE/SERT-IN-1 [2766739-35-7]
HY-146619
CAS Number2766739-35-7
Product group Chemicals
Molecular Weight637.28
Overview
- SupplierMedChem Express
- Product NameRAGE/SERT-IN-1 [2766739-35-7]
- Delivery Days Customer10
- CAS Number2766739-35-7
- CertificationResearch Use Only
- Molecular FormulaC38H41ClN4OS
- Molecular Weight637.28
- Scientific DescriptionRAGE/SERT-IN-1 is a potent and orally active advanced glycation end products (RAGE) and serotonin transporter (SERT) inhibitor with IC50s of 8.26 microM and 31.09 nM, respectively. RAGE/SERT-IN-1 exhibits significant neuroprotective effect against Abeta25-35-induced neuronal damage and alleviates depressive behavior of mice. RAGE/SERT-IN-1 can be used for researching the comorbidity of Alzheimers disease and depression[1].
- SMILESCCCCC1=C(N=C(S1)C2CCN(CC2)CCCCC3=CN(C4=C3C=C(C=C4)C#N)C)C5=CC=C(C=C5)OC6=CC=C(C=C6)Cl
- UNSPSC12131703